Is it possible to customize Android Screen?

The answer is yes, here is how to do :
http://www.pcworld.com/article/190257/customize_your_android_phone.html

Or Google at "customize android" and you will have pretty of how-to.
This is possible with widgets. Each home-screen panel can hold any combination of widgets, shortcuts, and folders. You can play around with different setups until you find the configuration that works best for you.


Customizing the LED Light/Flash
Most Android handsets have an LED indicator. By default, the LED usually flashes different colors to alert you to a missed call, to new e-mail, or to a new text message. But you can make the indicator do much more.
Expand your phone's notification functionality with Missed Call, a free app available in the Android Market. Missed Call harnesses the power of your handset's LED, letting you set the light to flash certain colors when specific events happen. You could, for instance, program it to flash orange when you miss a call from your boss and purple when you miss a call from your spouse; you could even set flashing LED colors to alert you to pending calendar events and other customizable circumstances.